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ARUP Free or Bioavailable Testosterone Test Options (Adult Females, Children, or Individuals on Testosterone-Suppressing Hormone Therapy)

Free or bioavailable testosterone tests may provide supportive information after a total testosterone test. The selection of a test may be based on clinical judgment and preference.

These tests are suitable for measuring a wide range of testosterone concentrations and are most useful when low concentrations are expected, regardless of the patient’s sex assigned at birth. Immunoassay-based tests may be more cost-effective if high testosterone concentrations, such as those found in cisgender males, are expected; refer to the Free or Bioavailable Testosterone Test Options (Adult Males or Individuals on Testosterone Hormone Therapy) table.

	Method				Results Reported
Test Name and Number	IA	MS	ED	Calc	Total T	Free T	Bio T	SHBG
Testosterone, Free (Adult Females, Children, or Individuals on Testosterone-Suppressing Hormone Therapy) 0081059		✔		✔		✔
Testosterone, Free and Total, Includes Sex Hormone-Binding Globulin (Adult Females, Children, or Individuals on Testosterone-Suppressing Hormone Therapy) 0081056		✔		✔	✔	✔		✔
Testosterone, Bioavailable and Total, Includes Sex Hormone-Binding Globulin (Adult Females, Children, or Individuals on Testosterone-Suppressing Hormone Therapy) 0081057		✔		✔	✔	✔	✔	✔
Bio, bioavailable; Calc, calculation; ED, equilibrium dialysis; IA, immunoassay; MS, mass spectrometry; SHBG, sex hormone-binding globulin; T, testosterone

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ARUP Free or Bioavailable Testosterone Test Options (Adult Females, Children, or Individuals on Testosterone-Suppressing Hormone Therapy)